Great Wolf Lodge coming to Northern California in 2020

The Central Valley has no idea how much fun it is about to have.

Save for the red paw print stamped on the massive resort building, Great Wolf Lodge looks like any other large family hotel. But, inside, this family of resorts houses the biggest indoor water park in the country. And now, it’s coming to Manteca.

The Chicago-based chain is opening the Northern California resort — its 19th — in the first half of 2020, bringing 95,000 square feet of splashing fun, 45,000 square feet of family entertainment, 500 rooms and wolf den-inspired suites as well as several eateries to the 26-acre property.

We checked out California’s first Great Wolf Lodge after it opened in Garden Grove, just a few miles from Disneyland, back in 2017. And let’s just say we almost had more fun with the Wolf than with the black-eared Mouse. Think body slides, tube slides, raft rides and activity pools heated to a comfy 84 degrees. It’s a dizzying array of options and the kids may never actually get their fill unless you stay for, like, a week.

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Source:: The Mercury News – Lifestyle

      

Sponsored: Natural beauty surrounds this Alamo sanctuary above Round Hill Country Club

Nothing but natural beauty exists between this hillside Alamo estate and the majestic Mount Diablo.

There are multiple terraces with grand views, plus a pair of centuries-old oak trees to admire.

Strategically and gracefully built to maximize the panoramic and awe-inspiring views, the home includes a wall of windows in the great room that collapse into the wall and opens to an amazing terrace. A pair of centuries-old oak trees perfectly frames the captivating view.

This two-story hillside home in Alamo features more than 6,000 square feet of living space.

Feel the tranquility of a private sanctuary wrapped in nature’s beauty high above Alamo’s Round Hill Country Club, yet easy proximity to downtown, freeways, airport access, and top-rated San Ramon Valley Unified School District schools.

Located at 446 Legacy Drive, the estate is one of 13 home sites in this exclusive gated enclave of custom homes. Built by general contractor David Newitt and Danville’s Miramar Homebuilders in 2015, it is masterfully crafted with an Old World design mingled with fresh and stylish features. The open and flowing floor plan bathed in natural light showcases large, spacious rooms, volume ceilings, oversize windows, and a calming neutral palette of colors that blends in beautifully with its surroundings. Wide-planked European natural oak hardwood, travertine flooring and smooth finished walls are featured throughout.

The two-story home features more than 6,000 square feet of living space with five bedrooms including a main-level grand master suite, four full bathrooms, two powder rooms, dedicated office, enormous bonus/media room with balcony, formal dining room, gourmet kitchen with casual dining nook, butler’s pantry and a wine cellar for 600-plus bottles.

The impressive entry through double glass doors decorated with ornamental ironwork opens onto the great room with a 22-foot beamed ceiling, and a 16-by-8-foot wall of windows that completely opens providing a seamless flow …read more

Source:: The Mercury News – Lifestyle

      

Arsenic may help treat cancer, studies show

Arsenic has long been notorious for its poisonous properties but now it is being investigated as a part of a cure for cancer.

A new study is exploring how some arsenic compounds, parsed out in carefully measured doses, might help treat cancer, as Medical News reports. That’s ironic because arsenic itself is a carcinogen, a substance whose presence in a person’s environment can lead to the development of cancer.

Researchers from the Beth Israel Deaconess Medical Center (BIDMC) in Boston, MA, are investigating the potential of arsenic trioxide, a compound in arsenic known as ATO, in treating cancer. ATO gained Food and Drug Administration (FDA) approval under the marketing name Trisenox in 2001. Drs. Kun Ping Lu, Xiao Zhen Zhou, and colleagues looked at how ATO in combination with another existing drug — all-trans retinoic acid (ATRA) — might actually be used to cure promyelocytic leukemia, a type of blood cancer. Their findings have been published in the journal Nature Communications.

A 2010 Stanford study drew similar conclusions that arsenic shows promises in treating a variety of cancers. Specifically combining arsenic with other therapies may give doctors a two-pronged approach to fighting forms of the disease caused by a malfunction in a critical cellular signaling cascade called the Hedgehog pathway.

“Arsenic might be especially effective for treating some types of cancers in combination with other drugs that act at different levels of the Hedgehog pathway, such as the cyclopamine mimics that pharmaceutical companies are developing,” said Philip Beachy, PhD, professor of developmental biology at the Stanford School of Medicine, as Stanford Medicine’s News Center reported.

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Source:: The Mercury News – Lifestyle

      

Heading for Yosemite? Here are some things you should know

If absence really makes the heart grow fonder, Yosemite is about to be embraced by a bear hug so huge that even the park’s bears will be amazed.

With much of Yosemite National Park off-limits to visitors since the nearby Ferguson Fire filled the valley with smoke in late July, the vacation plans of thousands have been put on hold, restructured or simply blown to smithereens.Related Articles

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And while some smoke still remains in the park, those days of closed roads and No Entry signs of almost over. Yosemite is reopening this week and here’s what you need to know:

The storied sequoia trees of Mariposa Grove will open today at 9 a.m..
The park’s central showpiece of Yosemite Valley – including Yosemite Valley Lodge, The Majestic Yosemite Hotel, Half Dome Village and Housekeeping Camp – will reopen Tuesday at 9 a.m..
Besides the smoke, you probably won’t see much of the Ferguson Fire’s burn area since its path was largely on Yosemite’s western flank; it’s in inaccessible areas of steep ravines, thick brush and dead standing timber that already had been destroyed by years of drought and a terrible bark-beetle infestation.
Starting at 9 a.m. Tuesday, visitors can enter the valley from El Portal Road (Highway 140), Big Oak Flat Road (Highway 120) or Tioga Road (Highway 120).
Visitors should expect limited hours and visitor services as the park returns to normal, park spokesman Scott Gediman said. “Park visitors should …read more

Source:: The Mercury News – Lifestyle

      

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